Dynactin 2 (p50) (DCTN2) (Middle Region) Peptide
DCTN2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5674014
发货至:
中国
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Contact Info
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Quick Overview for Dynactin 2 (p50) (DCTN2) (Middle Region) Peptide (ABIN5674014)
抗原
Dynamitin (DCTN2)
(Dynactin 2 (p50) (DCTN2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- EKLLGPDAAI NLTDPDGALA KRLLLQLEAT KNSKGGSGGK TTGTPPDSSL
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产品特性
- This is a synthetic peptide designed for use in combination with anti- DCTN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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背景
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This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: RBP50, DCTN50, HEL-S-77, DYNAMITIN
Protein Size: 401 -
基因ID
- 10540
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NCBI登录号
- NM_001261412, NP_001248341
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UniProt
- Q13561
抗原
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