Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptide
PES1
适用: 人
宿主: 合成
WB, BP
产品编号 ABIN5673777
发货至:
中国
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Contact Info
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Quick Overview for Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptide (ABIN5673777)
抗原
PES1
(Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
宿主
人
资源
合成
应用范围
Western Blotting (WB), Blocking Peptide (BP)
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蛋白结构域
- Middle Region
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序列
- LQRGEDPGNL NESEEEEEED DNNEGDGDEE GENEEEEEDA EAGSEKEEEA
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产品特性
- This is a synthetic peptide designed for use in combination with anti- PES1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
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背景
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This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
Alias Symbols: PES
Protein Size: 588 -
基因ID
- 23481
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NCBI登录号
- NM_001243225, NP_001230154
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UniProt
- O00541
抗原
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