Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (Middle Region) Peptide
SNRPN
适用: 人
宿主: 合成
BP, WB
Quick Overview for Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (Middle Region) Peptide (ABIN5673604)
抗原
SNRPN
(Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- TASIAGAPTQ YPPGRGTPPP PVGRATPPPG IMAPPPGMRP PMGPPIGLPP
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产品特性
- This is a synthetic peptide designed for use in combination with anti- SNRPN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
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背景
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This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome.
Alias Symbols: SMN, PWCR, SM-D, sm-N, RT-LI, HCERN3, SNRNP-N, SNURF-SNRPN
Protein Size: 240 -
基因ID
- 6638
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NCBI登录号
- NM_003097, NP_003088
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UniProt
- P63162
抗原
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