Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Middle Region) Peptide
RASSF1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Middle Region) Peptide (ABIN5673474)
抗原
RASSF1
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- IKVQLKLVRP VSVPSSKKPP SLQDARRGPG RGTSVRRRTS FYLPKDAVKH
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产品特性
- This is a synthetic peptide designed for use in combination with anti- RASSF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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背景
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: 123F2, RDA32, NORE2A, RASSF1A, REH3P21
Protein Size: 344 -
基因ID
- 11186
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NCBI登录号
- NM_001206957, NP_001193886
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UniProt
- Q9NS23
抗原
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