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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide

PINX1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5673446
发货至: 中国
  • 抗原 See all PINX1 products
    PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 9
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    LGLGATINNE DNWIAHQDDF NQLLAELNTC HGQETTDSSD KKEKKSFSLE
    产品特性
    This is a synthetic peptide designed for use in combination with anti- PINX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
    别名
    PINX1 Peptide, LPTL Peptide, LPTS Peptide, 2210403I16Rik Peptide, 2610028A01Rik Peptide, 67-11-3 Peptide, AU024023 Peptide, LPTS1 Peptide, RGD1566025 Peptide, PIN2/TERF1 interacting telomerase inhibitor 1 Peptide, PIN2/TERF1 interacting, telomerase inhibitor 1 Peptide, PINX1 Peptide, Pinx1 Peptide
    背景
    Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors. May be required for the survival of both hematopoietic and endothelial precursors during specification. Competes with GATA4 for binding and activation of the FGF3 promoter. Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.

    Alias Symbols: Gno1, LPTL, LPTS, Pxr1

    Protein Size: 440
    基因ID
    54984
    NCBI登录号
    NM_001284356, NP_001271285
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