PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide
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Quick Overview for PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide (ABIN5673446)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- LGLGATINNE DNWIAHQDDF NQLLAELNTC HGQETTDSSD KKEKKSFSLE
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产品特性
- This is a synthetic peptide designed for use in combination with anti- PINX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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背景
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Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors. May be required for the survival of both hematopoietic and endothelial precursors during specification. Competes with GATA4 for binding and activation of the FGF3 promoter. Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.
Alias Symbols: Gno1, LPTL, LPTS, Pxr1
Protein Size: 440 -
基因ID
- 54984
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NCBI登录号
- NM_001284356, NP_001271285
抗原
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