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Carbonic Anhydrase IX (CA9) (Middle Region) Peptide

CA9 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5672859
发货至: 中国
  • 抗原 See all CA9 products
    CA9 (Carbonic Anhydrase IX (CA9))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    KQLHTLSDTL WGPGDSRLQL NFRATQPLNG RVIEASFPAG VDSSPRAAEP
    产品特性
    This is a synthetic peptide designed for use in combination with anti- CA9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CA9 (Carbonic Anhydrase IX (CA9))
    背景
    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

    Alias Symbols: MN, CAIX

    Protein Size: 459
    基因ID
    768
    NCBI登录号
    NM_001216, NP_001207
    UniProt
    Q16790
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