Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Middle Region) Peptide
ITCH
适用: 人
宿主: 合成
BP, WB
Quick Overview for Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Middle Region) Peptide (ABIN5672845)
抗原
ITCH
(Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- Middle Region
-
序列
- KPSRPPRPSR PPPPTPRRPA SVNGSPSATS ESDGSSTGSL PPTNTNTNTS
-
产品特性
- This is a synthetic peptide designed for use in combination with anti- ITCH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
-
背景
-
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: AIF4, AIP4, ADMFD, NAPP1
Protein Size: 752 -
基因ID
- 83737
-
NCBI登录号
- NM_001257137, NP_001244066
抗原
-
You are here:
