Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptide
RGS14
适用: 人
宿主: 合成
BP, WB
Quick Overview for Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptide (ABIN5672630)
抗原
RGS14
(Regulator of G-Protein Signaling 14 (RGS14))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- ELLNRVQSSG AHDQRGLLRK EDLVLPEFLQ LPAQGPSSEE TPPQTKSAAQ
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产品特性
- This is a synthetic peptide designed for use in combination with anti- RGS14 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
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背景
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Protein Size: 347 -
基因ID
- 10636
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NCBI登录号
- NM_006480, NP_006471
抗原
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