Fibroblast Growth Factor Receptor 2 (FGFR2) (Middle Region) Peptide
FGFR2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5672562
发货至:
中国
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Contact Info
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Quick Overview for Fibroblast Growth Factor Receptor 2 (FGFR2) (Middle Region) Peptide (ABIN5672562)
抗原
FGFR2
(Fibroblast Growth Factor Receptor 2 (FGFR2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RNVLVTENNV MKIADFGLAR DINNIDYYKK TTNGRLPVKW MAPEALFDRV
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产品特性
- This is a synthetic peptide designed for use in combination with anti- FGFR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Fibroblast Growth Factor Receptor 2 (FGFR2) peptide
FGFR2 适用: 人, 小鼠, Cow, 犬, Pig, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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背景
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM
Protein Size: 707 -
基因ID
- 2263
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NCBI登录号
- NM_000141, NP_000132
抗原
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