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Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide

DAZL 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5672476
发货至: 中国
  • 抗原 See all DAZL products
    DAZL (Deleted in Azoospermia-Like (DAZL))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    EATPPSGNGP QKKSVDRSIQ TVVSCLFNPE NRLRNSVVTQ DDYFKDKRVH
    产品特性
    This is a synthetic peptide designed for use in combination with anti- DAZL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DAZL (Deleted in Azoospermia-Like (DAZL))
    别名
    DAZH Peptide, DAZL1 Peptide, DAZLA Peptide, SPGYLA Peptide, DAZL Peptide, Xdazl Peptide, dazh Peptide, dazl1 Peptide, dazla Peptide, spgyla Peptide, dazl-B Peptide, dazl-a Peptide, Daz-like Peptide, Dazh Peptide, Dazl1 Peptide, Dazla Peptide, Tpx-2 Peptide, Tpx2 Peptide, deleted in azoospermia like Peptide, deleted in azoospermia-like Peptide, deleted in azoospermia-like L homeolog Peptide, DAZL Peptide, dazl Peptide, Dazl Peptide, dazl.L Peptide
    背景
    The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: DAZH, DAZL1, DAZLA, SPGYLA

    Protein Size: 295
    基因ID
    1618
    NCBI登录号
    NM_001190811, NP_001177740
    UniProt
    Q92904
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