Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide
DAZL
适用: 人
宿主: 合成
BP, WB
Quick Overview for Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide (ABIN5672476)
抗原
DAZL
(Deleted in Azoospermia-Like (DAZL))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- EATPPSGNGP QKKSVDRSIQ TVVSCLFNPE NRLRNSVVTQ DDYFKDKRVH
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产品特性
- This is a synthetic peptide designed for use in combination with anti- DAZL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Deleted in Azoospermia-Like (DAZL) peptide
DAZL 适用: 人, 小鼠, Cow, 犬, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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背景
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The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DAZH, DAZL1, DAZLA, SPGYLA
Protein Size: 295 -
基因ID
- 1618
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NCBI登录号
- NM_001190811, NP_001177740
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UniProt
- Q92904
抗原
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