Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide
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Quick Overview for Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide (ABIN5672381)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- FTNPPQVATY HRAIKITVDG PREPRRHRQK LDDQTKPGSL SFSERLSELE
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产品特性
- This is a synthetic peptide designed for use in combination with anti- RUNX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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背景
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha
Protein Size: 250 -
基因ID
- 861
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NCBI登录号
- NM_001001890, NP_001001890
抗原
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