Arachidonate 5-Lipoxygenase (ALOX5) (Middle Region) Peptide
ALOX5
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5672355
发货至:
中国
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Contact Info
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Quick Overview for Arachidonate 5-Lipoxygenase (ALOX5) (Middle Region) Peptide (ABIN5672355)
抗原
ALOX5
(Arachidonate 5-Lipoxygenase (ALOX5))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RRKELETRQK QYRWMEWNPG FPLSIDAKCH KDLPRDIQFD SEKGVDFVLN
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产品特性
- This is a synthetic peptide designed for use in combination with anti- ALOX5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Arachidonate 5-Lipoxygenase (ALOX5) peptide
ALOX5 适用: 人, 大鼠, 犬, 小鼠 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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背景
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This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 5-LO, 5LPG, LOG5, 5-LOX
Protein Size: 484 -
基因ID
- 240
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NCBI登录号
- NM_000698, NP_000689
抗原
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