Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide
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Quick Overview for Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide (ABIN5672209)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST
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产品特性
- This is a synthetic peptide designed for use in combination with anti- FRS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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背景
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Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Alias Symbols: SNT, SNT1, FRS1A, FRS2A, SNT-1, FRS2alpha
Protein Size: 508 -
基因ID
- 10818
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NCBI登录号
- NM_001042555, NP_001036020
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UniProt
- Q8WU20
抗原
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