Myosin Phosphatase rho Interacting Protein (MPRIP) (N-Term) Peptide
MPRIP
适用: 人
宿主: 合成
BP, WB
Quick Overview for Myosin Phosphatase rho Interacting Protein (MPRIP) (N-Term) Peptide (ABIN5672104)
抗原
MPRIP
(Myosin Phosphatase rho Interacting Protein (MPRIP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- RTNKQNQKKK RKVEPPTPQE PGPAKVAVTS SSSSSSSSSS IPSAEKVPTT
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产品特性
- This is a synthetic peptide designed for use in combination with anti- MPRIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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背景
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Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Alias Symbols: MRIP, RIP3, M-RIP, RHOIP3, p116Rip
Protein Size: 1000 -
基因ID
- 23164
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NCBI登录号
- NM_015134, NP_055949
抗原
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