SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptide
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Quick Overview for SET Domain and Mariner Transposase Fusion Gene (SETMAR) (Middle Region) Peptide (ABIN5671864)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- VDPTYIGNIG RFLNHSCEPN LLMIPVRIDS MVPKLALFAA KDIVPEEELS
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产品特性
- This is a synthetic peptide designed for use in combination with anti- SETMAR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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背景
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This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Alias Symbols: Mar1, HsMar1, METNASE
Protein Size: 365 -
基因ID
- 6419
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NCBI登录号
- NM_001243723, NP_001230652
抗原
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