PR Domain Containing 16 (PRDM16) (Middle Region) Peptide
PRDM16
适用: 人
宿主: 合成
BP, WB
Quick Overview for PR Domain Containing 16 (PRDM16) (Middle Region) Peptide (ABIN5671793)
抗原
PRDM16
(PR Domain Containing 16 (PRDM16))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SAPASGEEQP LDLSIGSRAR ASQNGGGREP RKNHVYGERK LGAGEGLPQV
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产品特性
- This is a synthetic peptide designed for use in combination with anti- PRDM16 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRDM16 (PR Domain Containing 16 (PRDM16))
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背景
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The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MEL1, LVNC8, PFM13, CMD1LL
Protein Size: 1092 -
基因ID
- 63976
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NCBI登录号
- NM_022114, NP_071397
抗原
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