Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) Peptide
NRBF2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all NRBF2 products
- NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- EFLVAENERL RKENKQLKAE KARLLKGPIE KELDVDADFV ETSELWSLPP
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- NRBF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))
- 背景
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May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.
Alias Symbols: COPR, COPR1, COPR2, NRBF-2
Protein Size: 287 - 基因ID
- 29982
- NCBI登录号
- NM_001282405, NP_001269334
- UniProt
- Q96F24
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