MutS Homolog 6 (E. Coli) (MSH6) (Middle Region) Peptide
MSH6
适用: 人
宿主: 合成
BP, WB
Quick Overview for MutS Homolog 6 (E. Coli) (MSH6) (Middle Region) Peptide (ABIN5671696)
抗原
MSH6
(MutS Homolog 6 (E. Coli) (MSH6))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- MVVPDKISEV VELLKKLPDL ERLLSKIHNV GSPLKSQNHP DSRAIMYEET
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产品特性
- This is a synthetic peptide designed for use in combination with anti- MSH6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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背景
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This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Alias Symbols: GTBP, HSAP, p160, GTMBP, HNPCC5
Protein Size: 1360 -
基因ID
- 2956
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NCBI登录号
- NM_000179, NP_000170
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UniProt
- P52701
抗原
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