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Cortactin (CTTN) (Middle Region) Peptide

CTTN 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5671528
发货至: 中国

Quick Overview for Cortactin (CTTN) (Middle Region) Peptide (ABIN5671528)

抗原

Cortactin (CTTN)

宿主

资源

  • 13
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    YSSGFGGKYG VQADRVDKSA VGFDYQGKTE KHESQRDYSK GFGGKYGIDK

    产品特性

    This is a synthetic peptide designed for use in combination with anti- CTTN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    Cortactin (CTTN)

    背景

    This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

    Alias Symbols: EMS1

    Protein Size: 634

    基因ID

    2017

    NCBI登录号

    NM_001184740, NP_001171669
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