Activating Transcription Factor 7 (ATF7) (Middle Region) Peptide
ATF7
适用: 人
宿主: 合成
BP, WB
Quick Overview for Activating Transcription Factor 7 (ATF7) (Middle Region) Peptide (ABIN5671442)
抗原
ATF7
(Activating Transcription Factor 7 (ATF7))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- QILIQHPDAP SPAQPQVSPA QPTPSTGGRR RRTVDEDPDE RRQRFLERNR
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产品特性
- This is a synthetic peptide designed for use in combination with anti- ATF7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Activating Transcription Factor 7 (ATF7) peptide
ATF7 适用: 人, 大鼠, Cow, 犬 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF7 (Activating Transcription Factor 7 (ATF7))
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背景
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Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Alias Symbols: ATFA
Protein Size: 494 -
基因ID
- 11016
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NCBI登录号
- NM_001130060, NP_001123532
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UniProt
- P17544
抗原
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