3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Middle Region) Peptide
PDPK1
适用: 小鼠
宿主: 合成
BP, WB
Quick Overview for 3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Middle Region) Peptide (ABIN5671403)
抗原
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
宿主
小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- QYFLDRFYMS RISIRMLLNQ HSLLFGGKGS PSHRKHIGSI NPNCDVVEVI
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产品特性
- This is a synthetic peptide designed for use in combination with anti- PDK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) peptide
PDPK1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
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背景
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Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress (By similarity).
Alias Symbols: B830012B01, D530020C15Rik
Protein Size: 434 -
基因ID
- 228026
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NCBI登录号
- NM_172665, NP_766253
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UniProt
- Q8BFP9
抗原
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