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3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (Middle Region) Peptide

PDPK1 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN5671403
发货至: 中国
  • 抗原 See all PDPK1 products
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    蛋白结构域
    Middle Region
    宿主
    小鼠
    资源
    • 9
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QYFLDRFYMS RISIRMLLNQ HSLLFGGKGS PSHRKHIGSI NPNCDVVEVI
    产品特性
    This is a synthetic peptide designed for use in combination with anti- PDK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    背景
    Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress (By similarity).

    Alias Symbols: B830012B01, D530020C15Rik

    Protein Size: 434
    基因ID
    228026
    NCBI登录号
    NM_172665, NP_766253
    UniProt
    Q8BFP9
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