Hemoglobin C Peptide
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北京 101111
Quick Overview for Hemoglobin C Peptide (ABIN5624621)
抗原
资源
应用范围
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蛋白类型
- Synthetic
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Supplier Product No.
- 000-001-gs7
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Supplier
- Rockland
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原理
- HbC Control Peptide
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产品特性
- HbC Control Peptide, Hemoglobin beta subunit C variant, HbBc, HbC, Sickle Cell Disease (SCD)
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纯化方法
- Greater than 95% specific peptide
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纯度
- Greater than 95% specific peptide
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应用备注
- Optional[Flow Cytometry Dilution]: HbC peptide can be used as a control with the HbC antibody. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 6 months
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- Hemoglobin C
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背景
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Synonyms: HbC Control Peptide, Hemoglobin beta subunit C variant, HbBc, HbC, Sickle Cell Disease (SCD)
Background: HbC peptide corresponds to the E6K mutant in the amino-terminal portion of hemoglobin beta subunit. Functional hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Less significant than the SCD-E6V, HbC E6K mutation causes a mild hemolytic anemia. HbC peptide is suitable for use as a control with the HbC antibody. This peptide is ideal for investigators involved in Cardiovascular and developmental biology research.
抗原
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