Fetal Hemoglobin (HbF) Peptide
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北京 101111
Quick Overview for Fetal Hemoglobin (HbF) Peptide (ABIN5624580)
抗原
资源
应用范围
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蛋白类型
- Synthetic
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Supplier Product No.
- 000-001-gs6
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Supplier
- Rockland
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原理
- HbF Control Peptide
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产品特性
- HbF Control Peptide, Hemoglobin delta subunit, HBG1, HBG2, Sickle Cell Disease (SCD)
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纯化方法
- Greater than 95% specific peptide
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纯度
- Greater than 95% specific peptide
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应用备注
- Optional[Flow Cytometry Dilution]: HbF peptide can be used as a control with the HbF antibody. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 6 months
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- Fetal Hemoglobin (HbF)
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背景
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Synonyms: HbF Control Peptide, Hemoglobin delta subunit, HBG1, HBG2, Sickle Cell Disease (SCD)
Background: HbF peptide corresponds to the hemoglobin gamma isoform subunit amino terminal region. Functional alternate hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 gamma subunits. Hemoglobin F is elevated in newborns, reaching adult levels by 12 months. HbF levels are increased to as much as 5 % to 10 % in normal pregnancy. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Hemoglobin variants arise from mutations in the globin genes and sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. HbF peptide is suitable as a control when used with Anti-HbF antibody. This peptide is ideal for investigators involved in Cardiovascular and developmental biology research.
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基因ID
- 3047
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NCBI登录号
- NP_000550
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UniProt
- P69891
抗原
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