Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) (Middle Region) Peptide
MAPKAPK5
适用: 人
宿主: 合成
WB
Quick Overview for Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) (Middle Region) Peptide (ABIN5518501)
抗原
MAPKAP Kinase 5 (MAPKAPK5)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
宿主
人
资源
合成
应用范围
Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- TPYTYNKSCD LWSLGVIIYV MLCGYPPFYS KHHSRTIPKD MRRKIMTGSF
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
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背景
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The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: MK5, MK-5, PRAK, MAPKAP-K5
Protein Size: 473 -
基因ID
- 8550
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NCBI登录号
- NM_003668, NP_003659
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UniProt
- Q8IW41
抗原
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