BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Middle Region) Peptide
BCL2L11
适用: 人
宿主: 合成
WB
产品编号 ABIN5518496
发货至:
中国
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中国
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Quick Overview for BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (Middle Region) Peptide (ABIN5518496)
抗原
BIM (BCL2L11)
(BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
宿主
人
资源
合成
应用范围
Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- PAERPPQLRP GAPTSLQTEP QGNPEGNHGG EGDSCPHGSP QGPLAPPASP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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背景
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The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
Alias Symbols: BAM, BIM, BOD
Protein Size: 198 -
基因ID
- 10018
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NCBI登录号
- NM_001204106, NP_001191035
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UniProt
- O43521
抗原
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