Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide
CIDEA
适用: 人
宿主: 合成
WB
Quick Overview for Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide (ABIN5518475)
抗原
CIDEA
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
宿主
人
资源
合成
应用范围
Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RPFRVSNHDR SSRRGVMASS LQELISKTLD ALVIATGLVT LVLEEDGTVV
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
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背景
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This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Alias Symbols: CIDE-A,
Protein Size: 219 -
基因ID
- 1149
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NCBI登录号
- NM_001279, NP_001270
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UniProt
- O60543
抗原
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