Hepcidin Antimicrobial Peptide (HAMP) (Middle Region) Peptide
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Quick Overview for Hepcidin Antimicrobial Peptide (HAMP) (Middle Region) Peptide (ABIN5518385)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- WAACLLLLLL LASLTSGSVF PQQTGQLAEL QPQDRAGARA SWMPMFQRRR
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Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)
HAMP 适用: 人 宿主: 合成 WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP 适用: Cow 宿主: 合成 WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP 适用: 人 宿主: 合成 WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP 适用: Cow 宿主: 合成 WB, Imm, SDS
Hepcidin Antimicrobial Peptide (HAMP) peptide (Ovalbumin)HAMP 适用: 人 宿主: 合成 WB, Imm, SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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背景
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The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
Alias Symbols: HEPC, PLTR, HFE2B, LEAP1
Protein Size: 113 -
基因ID
- 57817
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NCBI登录号
- NM_021175, NP_066998
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UniProt
- P81172
抗原
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