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Hepcidin Antimicrobial Peptide (HAMP) (Middle Region) Peptide

HAMP 适用: 人 宿主: 合成 WB
产品编号 ABIN5518385
发货至: 中国
  • 抗原 See all Hepcidin (HAMP) products
    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 11
    合成
    应用范围
    Western Blotting (WB)
    序列
    WAACLLLLLL LASLTSGSVF PQQTGQLAEL QPQDRAGARA SWMPMFQRRR
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
    背景
    The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

    Alias Symbols: HEPC, PLTR, HFE2B, LEAP1

    Protein Size: 113
    基因ID
    57817
    NCBI登录号
    NM_021175, NP_066998
    UniProt
    P81172
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