Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide
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Quick Overview for Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide (ABIN5518321)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- SAPARLYHKK VVDHYENPRN VGSLDKTSKN VGTGLVGAPA CGDVMKLQIQ
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
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背景
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Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HML, ISU2, NIFU, NIFUN, hnifU, 2310020H20Rik
Protein Size: 167 -
基因ID
- 23479
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NCBI登录号
- NM_014301, NP_055116
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UniProt
- Q9H1K1
抗原
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