TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptide
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Quick Overview for TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) Peptide (ABIN5518223)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- MLMDQGSSRR HLGDAFKPDP NSSSFKKPTG EMNIASGCPV FVAQTVLENG
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))
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背景
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The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Alias Symbols: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp
Protein Size: 167 -
基因ID
- 7187
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NCBI登录号
- NM_001199427, NP_001186356
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UniProt
- Q13114
抗原
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