Single-Minded Homolog 2 (SIM2) (Middle Region) Peptide
SIM2
适用: 人
宿主: 合成
WB
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- 抗原 See all SIM2 products
- SIM2 (Single-Minded Homolog 2 (SIM2))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Western Blotting (WB)
- 序列
- SWRTALSTSQ ETRKLVKPKN TKMKTKLRTN PYPPQQYSSF QMDKLECGQL
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SIM2 (Single-Minded Homolog 2 (SIM2))
- 背景
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM, bHLHe15, HMC13F06, HMC29C01
Protein Size: 167 - 基因ID
- 6493
- NCBI登录号
- NM_005069, NP_005060
- UniProt
- Q14190
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