Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (N-Term) Peptide
FGR
适用: 人
宿主: 合成
WB
产品编号 ABIN5518129
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (N-Term) Peptide (ABIN5518129)
抗原
Fgr (FGR)
(Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
宿主
人
资源
合成
应用范围
Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- GDFRSYGAAD HYGPDPTKAR PASSFAHIPN YSNFSSQAIN PGFLDSGTIR
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Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) peptide
FGR 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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背景
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This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: SRC2, c-fgr, c-src2, p55-Fgr, p58-Fgr, p55c-fgr, p58c-fgr,
Protein Size: 167 -
基因ID
- 2268
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NCBI登录号
- NM_001042729, NP_001036194
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UniProt
- P09769
抗原
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