Sestrin 1 (SESN1) (Middle Region) Peptide
SESN1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SESN1 products
- SESN1 (Sestrin 1 (SESN1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- KRESMFVFSS DDEEVTPARA VSRHFEDTSY GYKDFSRHGM HVPTFRVQDY
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- SESN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SESN1 (Sestrin 1 (SESN1))
- 背景
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This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: PA26, SEST1
Protein Size: 492 - 基因ID
- 27244
- NCBI登录号
- NM_001199933, NP_001186862
- UniProt
- Q9Y6P5
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