Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (C-Term) Peptide
PLOD2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) (C-Term) Peptide (ABIN5513667)
抗原
PLOD2
(Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- PIFSEKACDE LVEEMEHYGK WSGGKHHDSR ISGGYENVPT DDIHMKQVDL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PLOD2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
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背景
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The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PLOD2,
Protein Size: 737 -
基因ID
- 5352
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UniProt
- O00469
抗原
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