sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptide
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北京 101111
Quick Overview for sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptide (ABIN5513637)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- PGEATAVEWG PNTWMVEYGR GVIPSTLAFA LADTVFSTQD FLTLFYTLRS
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产品特性
- This is a synthetic peptide designed for use in combination with anti- SIGMAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
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背景
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This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1
Protein Size: 223 -
基因ID
- 10280
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NCBI登录号
- NM_001282205, NP_001269134
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UniProt
- Q99720
抗原
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