Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide
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Quick Overview for Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide (ABIN5513592)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTRVLY
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产品特性
- This is a synthetic peptide designed for use in combination with anti- TMED10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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背景
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: p23, TMP21, S31I125, Tmp-21-I, S31III125, P24(DELTA)
Protein Size: 219 -
基因ID
- 10972
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NCBI登录号
- NM_006827, NP_006818
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UniProt
- P49755
抗原
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