Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide
TMED10
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TMED10 products
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTRVLY
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- TMED10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
- 背景
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: p23, TMP21, S31I125, Tmp-21-I, S31III125, P24(DELTA)
Protein Size: 219 - 基因ID
- 10972
- NCBI登录号
- NM_006827, NP_006818
- UniProt
- P49755
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