RAD51 Homolog B (Rad51B) (Middle Region) Peptide
Rad51B
适用: 人
宿主: 合成
BP, WB
Quick Overview for RAD51 Homolog B (Rad51B) (Middle Region) Peptide (ABIN5513536)
抗原
RAD51 Homolog B (Rad51B)
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- EFDAQLQGNL KERNKFLARE ASSLKYLAEE FSIPVILTNQ ITTHLSGALA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RAD51B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAD51 Homolog B (Rad51B)
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背景
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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Alias Symbols: REC2, R51H2, RAD51L1
Protein Size: 279 -
基因ID
- 5890
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NCBI登录号
- NP_002868
抗原
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