电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) (Middle Region) Peptide

PDHA1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5513490
发货至: 中国
  • 抗原 See all PDHA1 products
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    AASTDYYKRG DFIPGLRVDG MDILCVREAT RFAAAYCRSG KGPILMELQT
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PDHA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))
    背景
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PDHA, PDHAD, PHE1A, PDHCE1A

    Protein Size: 390
    基因ID
    5160
    NCBI登录号
    NM_000284, NP_000275
    UniProt
    P08559
You are here:
客服