NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide
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Quick Overview for NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide (ABIN5513462)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NSUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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背景
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NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Alias Symbols: NSUN2,SAKI, TRM4,
Protein Size: 767 -
基因ID
- 54888
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NCBI登录号
- NP_060225
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UniProt
- Q08J23
抗原
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