Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (Middle Region) Peptide
MMP12
适用: 人
宿主: 合成
BP, WB
Quick Overview for Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (Middle Region) Peptide (ABIN5513418)
抗原
MMP12
(Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RGIQSLYGDP KENQRLPNPD NSEPALCDPN LSFDAVTTVG NKIFFFKDRF
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MMP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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背景
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This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.
Alias Symbols: ME, HME, MME, MMP-12
Protein Size: 470 -
基因ID
- 4321
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NCBI登录号
- NM_002426, NP_002417
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UniProt
- P39900
抗原
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