Megakaryocyte-Associated tyrosine Kinase (MATK) (C-Term) Peptide
MATK
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5513404
发货至:
中国
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Quick Overview for Megakaryocyte-Associated tyrosine Kinase (MATK) (C-Term) Peptide (ABIN5513404)
抗原
MATK
(Megakaryocyte-Associated tyrosine Kinase (MATK))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MATK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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背景
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The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Alias Symbols: MATK, CTK, HYL,
Protein Size: 507 -
基因ID
- 4145
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NCBI登录号
- NP_647612
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UniProt
- P42679
抗原
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