Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptide
IFIH1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptide (ABIN5513096)
抗原
IFIH1
(Interferon Induced with Helicase C Domain 1 (IFIH1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK KKKASEPGKV IV
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产品特性
- This is a synthetic peptide designed for use in combination with anti- IFIH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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背景
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Alias Symbols: AGS7, Hlcd, MDA5, MDA-5, RLR-2, IDDM19, SGMRT1
Protein Size: 1025 -
基因ID
- 64135
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NCBI登录号
- NM_022168, NP_071451
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UniProt
- Q9BYX4
抗原
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