Insulin Induced Gene 1 (INSIG1) (Middle Region) Peptide
INSIG1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5513077
发货至:
中国
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Quick Overview for Insulin Induced Gene 1 (INSIG1) (Middle Region) Peptide (ABIN5513077)
抗原
INSIG1
(Insulin Induced Gene 1 (INSIG1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- LAAHGAPDAD PAPRGRSAAM SGPEPGSPYP NTWHHRLLQR SLVLFSVGVV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-INSIG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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背景
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Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: CL6, CL-6
Protein Size: 277 -
基因ID
- 3638
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NCBI登录号
- NM_005542, NP_005533
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UniProt
- O15503
抗原
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