Glutathione S-Transferase alpha 3 (GSTA3) (N-Term) Peptide
GSTA3
适用: 人
宿主: 合成
BP, WB
Quick Overview for Glutathione S-Transferase alpha 3 (GSTA3) (N-Term) Peptide (ABIN5513036)
抗原
GSTA3
(Glutathione S-Transferase alpha 3 (GSTA3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- N-Term
-
序列
- FEEKFIGSAE DLGKLRNDGS LMFQQVPMVE IDGMKLVQTR AILNYIASKY
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-GSTA3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
-
背景
-
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3,
Protein Size: 222 -
基因ID
- 2940
-
NCBI登录号
- NP_000838
-
UniProt
- Q16772
抗原
-
You are here:
