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Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide

CDKN1C 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512971
发货至: 中国
  • 抗原 See all CDKN1C products
    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    ELSRELQARL AELNAEDQNR WDYDFQQDMP LRGPGRLQWT EVDSDSVPAF
    产品特性
    This is a synthetic peptide designed for use in combination with anti- CDKN1C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
    别名
    BWCR Peptide, BWS Peptide, KIP2 Peptide, WBS Peptide, p57 Peptide, p57Kip2 Peptide, cb961 Peptide, p27Xic1-a Peptide, zgc:86618 Peptide, AL024410 Peptide, CDKI Peptide, Kip2 Peptide, p57(kip2) Peptide, p57KIP2 Peptide, cyclin dependent kinase inhibitor 1C Peptide, cyclin-dependent kinase inhibitor 1Ca Peptide, cyclin-dependent kinase inhibitor 1C (P57) Peptide, cyclin-dependent kinase inhibitor 1C Peptide, CDKN1C Peptide, cdkn1ca Peptide, Cdkn1c Peptide
    背景
    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2

    Protein Size: 316
    基因ID
    1028
    NCBI登录号
    NM_000076, NP_000067
    UniProt
    P49918
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