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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptide

LAIR1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512951
发货至: 中国
  • 抗原 See all LAIR1 products
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    蛋白结构域
    C-Term
    宿主
    资源
    • 5
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    HRQNQIKQGP PRSKDEEQKP QQRPDLAVDV LERTADKATV NGLPEKDRET
    产品特性
    This is a synthetic peptide designed for use in combination with anti-LAIR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    背景
    The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

    Alias Symbols: LAIR1,CD305,

    Protein Size: 287
    基因ID
    3903
    UniProt
    Q6GTX8
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