B-Cell Linker (BLNK) (N-Term) Peptide
BLNK
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all B-Cell Linker (BLNK) products
- B-Cell Linker (BLNK)
- 蛋白结构域
- N-Term
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- ADEEEQWSDD FDSDYENPDE HSDSEMYVMP AEENADDSYE PPPVEQETRP
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- BLNK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- B-Cell Linker (BLNK)
- 背景
-
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: bca, AGM4, BASH, LY57, SLP65, BLNK-S, SLP-65
Protein Size: 456 - 基因ID
- 29760
- NCBI登录号
- NM_001114094, NP_001107566
- UniProt
- Q8WV28
-
You are here:
