Adenomatous Polyposis Coli (APC) (Middle Region) Peptide
APC
适用: 人
宿主: 合成
BP, WB
Quick Overview for Adenomatous Polyposis Coli (APC) (Middle Region) Peptide (ABIN5512735)
抗原
APC
(Adenomatous Polyposis Coli (APC))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SETFDNIDNL SPKASHRSKQ RHKQSLYGDY VFDTNRHDDN RSDNFNTGNM
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产品特性
- This is a synthetic peptide designed for use in combination with anti-APC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- APC (Adenomatous Polyposis Coli (APC))
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背景
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This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Alias Symbols: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46
Protein Size: 1304 -
基因ID
- 324
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NCBI登录号
- NM_000038, NP_000029
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UniProt
- E9PFT7
抗原
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